NFKB1 and chronic obstructive pulmonary disease: Citing ergosterol for instance, the main bioactive ingredient in Cordyceps sinensis (C. sinensis), suppressed COPD inflammatory, oxidative stress, and apoptosis in both CSE-induced 16HBE cells and Balb/c mice via inhibiting the activation of NF-κB/p65, suggesting that ergosterol may be partially responsible for the therapeutic effects on COPD patients (Sun et al., 2019).