There was a modest difference in the genotype distribution of PD patients compared with the age- and sex-matched control subgroup (p = 0.04) in the nonsynonymous variant of TLR4 (c.896A > G p. D 299G; rs4986790), and the frequency of the G allele was higher in the PD group (odds ratio (OR) = 3.03, 95% CI j = 1.03–9.45, p = 0.04) (Supplementary Table S2). The gene discussed is TLR4; the disease is Parkinson disease.