Likewise, natural products (e.g., resveratrol, flavopiridol, indirubin, magnolol, piceatannol, parthenolide, EGCG, cucurbitacin Q, and curcumin) have been demonstrated to downregulate the activity of STAT3 in cancer cells (Arshad et al., 2020). This evidence concerns the gene STAT3 and cancer.