STAT3 and neoplasm: Curcumin also has an impact on numerous growth factor receptors and adhesion molecules that are implicated in tumor growth, angiogenesis, and metastasis (Wilken et al., 2011) and exerts antitumor action in cancer cells by the suppression of NF-κB and signal transducers and activators of the transcription 3 (STAT3) pathways (Jiménez-Flores et al., 2014).