In addition, administration of muscimol (Lee et al., 2011) to microglia stimulated with lipopolysaccharide (LPS)/interferon-γ, the latter typically shows elevated levels following stroke (Kuric and Ruscher, 2014) significantly reduced the level of pro-inflammatory cytokines interleukin 6 (IL-6) and tumor necrosis factor alpha (TNFα). Here, TNF is linked to Stroke.