RPA1 and infection: During early-stage infection, bacterial genes involved with nucleic acid biosynthesis were upregulated including ribonucleoside-diphosphate reductase subunit alpha (nrdA) and subunit beta (nrdB), single-stranded DNA-binding protein (ssbB), DNA helicase IV (helD), and putative transcriptional regulator (TetR/AcrR family) (ycnC).