Similarly, a-smooth muscle actin (a-SMA), collagen type 1 Alpha 1 (col1a1), collagen type 3 Alpha 1 (col3a1), and glial fibrillary acidic protein in HSCs, and mouse EGF-like module-containing mucin-like hormone receptor-like (EMR1 or F4/80) are enriched in KCs. This evidence concerns the gene ADGRE1 and dry eye syndrome.