CYP11B1 and adrenal cortex adenoma: The left adrenal adenoma showed CYP11B1-positive and CYP11B2-negative staining and harbored the <i>PRKACA-</i>L206R mutation.<h4>Conclusion</h4>In a PA patient with concomitant ACS, bilateral APM could coexist with both histopathologically classical and non-classical PA adenomas, each with different somatic mutations.