First, based on 938 BC patients, we used LASSO and 10-fold cross-validation to screen out nine indicators (Figure S1), included Tcell, helper T cell, killer T cell, B cell, NLR, LMR, CEA, CA125, and CA153 (Figure 4B, lambda.min=0.006644068). The gene discussed is CEACAM5; the disease is breast cancer.