MTOR and gastric cancer: Moreover, based on the ceRNAs hypothesis put forward by Tay et al. 19 in 2014, lncRNAs could competitively bind to miRNA to regulate gene expression, a plethora of evidences have thereafter proved the crucial role of miRNAs in alleviating the elevation of lncRNAs during tumor progression, such as PC 34, 35, gastric cancer 36 and ovarian cancer 37, etc. Besides, Lu et al. 38 also illustrated that LINC-DANCR could act as a ceRNA for miR-496 to mediate the expression of mTOR to modulate lung adenocarcinoma progression.