The representative images of CCT3 expression of melanoma and adjacent normal skin tissues are shown in Figure 1A. As illustrated in Figure 1B, significantly increased CCT3 expression (CCT3-high) was found in 67.5% (27/40) of melanoma samples, whereas high CCT3 expression was only observed in 40.0% (16/40) of the paired adjacent normal skin tissues. Here, CCT3 is linked to melanoma.