ONP-302 treatment had no effect on the number of TAMs (CD11b+F4/80+) in both LLC and MC-38 tumors; however, we observed a statistically significant increase in the number of M-MDSCs (CD11b+/Ly6Chi/Ly6G-) per gram of tumor after ONP-302 treatment in both LLC (p=0.01) and MC-38 tumors (p=0.01). Here, ITGAM is linked to neoplasm.