For further exploring the specific targeting effect of pcTERT-Noxa or pcTERT-Puma towards cancer cells, normal liver cells HL-7702 were used as a control and the same transfection procedure as mentioned above by using pcTERT-Noxa or pcTERT-Puma for 24 h, 48 h and 72 h was repeated. The gene discussed is BBC3; the disease is cancer.