Of these, BCLC staging B vs 0-A (hazard ratio(HR): 2.350, 95% confidence interval (CI):1.222-4.531; P = 0.010) and staging C vs 0-A (HR: 3.652, 95%CI: 1.212-11.184; P = 0.022), treatment -TACE ( HR: 2.693, 95%CI: 1.824-3.987; P < 0.001), tumour size ≥3cm (HR: 2.239, 95%CI: 1.452-3.459; P < 0.001), ɣ-GGT ≥60 (HR: 1.685, 95%CI: 1.100-2.579; P = 0.016), AFP ≥400 ( HR: 2.681, 95%CI: 1.692-4.248; P < 0.001) and CRP ≥5 (HR: 3.560, 95%CI: 2.361-5.388; P < 0.001) are independently correlated with MVI. This evidence concerns the gene CRP and neoplasm.