At a practical level, the fact that MELF-type invasion ECs stained strongly with CK19 could encourage the use of this staining as an additional immunohistochemical marker, which may be helpful in showing the extent of myometrial spread, including the unremarkable attenuated glands and single infiltrating cells that often extend beyond the promptly evident conventional tumor areas 81. The gene discussed is KRT19; the disease is neoplasm.