In lung adenocarcinoma (LUAD), serine/threonine kinase 11 (STK11) and Kelch-like ECH-associated protein 1 (KEAP1) co-mutant status strongly predict poor survival, which is associated with significantly elevated ferroptosis-protective gene expression and less vulnerability to ferroptosis (Wohlhieter et al., 2020). This evidence concerns the gene KEAP1 and lung adenocarcinoma.