MTOR and posterior cortical atrophy: Although normal cells have a mechanism to inhibit fatty acid synthesis if a determined concentration of fatty acids is present in the blood, PCa cells are insensitive to this mechanism and carry out lipidic biosynthesis due to the increased expression of lipogenesis enzymes regulated by the PI3K/AKT/mTOR, HER2/neu, and AR pathways (Wu et al., 2014).