Additionally, BRD4 was found to be enriched at SEs surrounding (upstream, downstream, or within) AXL, EHF, FOXM1, IGF1R, RAD51B, RAD51D, STAT6, and TRIB3 genes, most of which are linked to HCC pathogenesis (Adamek and Kasprzak, 2018; Shen et al., 2019; Qi et al., 2020; Batur et al., 2021; Luan et al., 2021). This evidence concerns the gene TRIB3 and hepatocellular carcinoma.