We have previously established the C. elegans pharynx for the analysis of arrhythmogenic CPVT-mutations, but also of Long QT-8 mutations affecting the CaV1.2 voltage-gated calcium channel (Schuler et al., 2015; Fischer et al., 2017). Here, CACNA1C is linked to catecholaminergic polymorphic ventricular tachycardia.