Consistently, RT‐qPCR analysis confirmed the significantly decreased expression of LINC01431 in HCC para‐tumor tissues from HBV‐positive HCC patients than that from HBV‐negative patients, and the levels of LINC01431 showed a significantly negative correlation with the levels of pregenomic RNA (pgRNA) in HBV‐positive HCC patients (Figure 1G). This evidence concerns the gene LINC01431 and neoplasm.