Analyzing the expression of the epithelial cell surface marker EpCAM by flow cytometry in the 8 Trp53 KO iKrasG12D tumors, we found 3 types of KrasG12D tumors: a predominantly EpCAMhigh tumor, a predominantly EpCAMlow tumor, and a mixed tumor with similar proportions of EpCAMhigh and EpCAMlow cells. This evidence concerns the gene EPCAM and neoplasm.