ASGR1 and metabolic dysfunction-associated steatohepatitis: In a diet-induced mouse model of NASH, Li et al. [33] followed changes in circulating EVs derived from hepatocytes (ASGR1 + , CYP2E1 +), macrophages (Galectin 3 +), neutrophils (Ly-6G/6C +) and platelets (CD61 +).