Although UBTF::ATXN7L3-specific gene expression showed little overlap with published CDX2 overexpression models (Supplementary Fig. S5A), we identified a functional module relating CDX2 to HOXA9 and MEIS1 overexpression in UBTF::ATXN7L3 ALL, in line with similar findings in AML [13] (Supplementary Figure S5B,C). This evidence concerns the gene MEIS1 and acute lymphoblastic leukemia.