Laboratory results evidenced a partially compensated metabolic acidosis (pH: 7.22; PaCO2: 17 mmHg; base excess: − 18 mmol/L), very severe hyperlactatemia (18 mmol/L), hyperleukocytosis (20 G/L) without lymphopenia, DIC with thrombocytopenia (7 G/L) and low prothrombin time (53%), and acute renal failure (serum creatinine: 354 μmol/L). This evidence concerns the gene F2 and acute kidney injury.