To date, however, a definite diagnosis can only be made based on autopsied alpha-synuclein (α-Syn) deposition in neurons as Lewy bodies in PD (Dufty et al., 2007) or in oligodendrocytes as glial cytoplasmic inclusions (GCIs) in MSA (Tu et al., 1998). Here, SNCA is linked to Parkinson disease.