In both the FCx and TCx, Ang-II was also unchanged in AD compared to controls (unpaired t test; p = .24 and unpaired t test; p = .96, repsectively; Figure 4E and G) and was unaltered in relation to Braak tangle stage (Tukey’s; BS 0–II vs III–IV p = .55, BS III–IV vs V–VI p = .89 and Tukey’s; BS 0–II vs III–IV p = 1.0, BS III–IV vs V–VI p = .10, respectively; Figure 4F and H). The gene discussed is AGT; the disease is Alzheimer disease.