IL6 and malaria: Subgroup analysis of continents showed that the mean IL-6 levels were higher in patients with uncomplicated malaria than in controls among studies conducted in Africa (P = 0.028, WMD = 41.68 pg/mL, 95% CI = 4.45–78.91 pg/mL, I2 = 100%, 11 studies) and Asia (P = 0.003, WMD = 75.04 pg/mL, 95% CI = 24.97−125.11 pg/mL, I2 = 99.7%, two studies).