Our met-analysis results showed no difference in IL-6 levels between patients with uncomplicated malaria and those with asymptomatic malaria and this might be due to the differences in the parasite density of patients with asymptomatic malaria as the mean parasitemia of patients with asymptomatic malaria was the lowest (mean 11.4 parasites per microliter) in a study conducted in Brazil31. The gene discussed is IL6; the disease is parasitic infectious disease.