CEACAM5 and neoplasm: Other independent factors, however, such as age12,13, gender13, race14, performance status15, carbohydrate antigen 19-9 (CA 19-9)16, carcinoembryonic antigen (CEA)15, tumor site17,18, metachronous or synchronous metastasis19, and treatment20,21 can also influence the survival of SBA patients significantly.