These studies confirmed that prophylactic inhibition of RAGE by pretreating the chips with either 20 or 100 nM azeliragon prevented the increase in cytokine production (Fig. 7b), although we observed that treatment with the higher dose resulted in a higher viral load (viral NP mRNA levels) when analyzed 48 h following infection (Fig. 7c). The gene discussed is AGER; the disease is infection.