However, none of the glycaemic traits had a substantial effect on breast cancer risk (fasting insulin OR: 1.00 [0.58:1.72], fasting glucose OR: 1.03 [0.85: 1.25], Hba1c OR: 1.02 [0.74: 1.4], HOMA-B OR: 1.06 [0.78: 1.45]. The gene discussed is INS; the disease is breast carcinoma.