In addition, elevated levels of hnRNP C in metastatic colon cancer cells drive coding region (CR) and UTR APA of a group of genes, including methylenetetrahydrofolate dehydrogenase (NADP+-dependent) 1-like (MTHFD1L), and these changes are closely associated with cancer progression [41]. This evidence concerns the gene MTHFD1L and malignant colon neoplasm.