In the nervous system, hnRNP C binds with a 29-nt sequence in the 3′-UTR of amyloid precursor protein (APP) mRNA, whose cleavage product Aβ is highly correlated with degenerative neuropathy, such as Alzheimer’s disease, and regulates neuronal synapse growth [84–88]. This evidence concerns the gene APP and early-onset autosomal dominant Alzheimer disease.