TBK1 and pigmentary glaucoma: Copy-number gains of the TBK1 gene have been associated with normal-tension glaucoma and a single case of exfoliation glaucoma, but TBK1 does not appear to be involved in the pathogenesis of high-tension glaucoma; available data additionally suggest TBK1 is not involved in the pathogenesis of juvenile-onset open-angle glaucoma, pigmentary glaucoma, nor steroid-induced glaucoma, but further studies are necessary to confirm this [36–38].