LDHA and non-small cell lung carcinoma: Moreover, subpopulations from H460, A549, and H226B cells were obtained by increasing the activity of aldehyde dehydrogenase (ALDH) [48] (Fig. 2o), another general property of CSCs, and these cells consistently possessed upregulated Ninj1 protein (Fig. 2p) and mRNA (Fig. 2q) expression levels of Ninj1 compared to levels in ALDHlow subpopulations and their corresponding NSCLC cells.