NINJ1 and colonic neoplasm: Given that Ninj1 is overexpressed in a range of histologically distinct epithelial tumors, including lung, breast, and colon cancers, and that the role of the Wnt/β-catenin signaling pathway in human cancers in general [9, 10, 14], the pathophysiological role of Ninj1 has been implicated in various human cancers.