Our subsequent findings using Ninj1high and Ninj1low subpopulations from NSCLC cell lines and PDX tumors revealed a positive correlation between Ninj1 expression and the functional features of CSCs (i.e., high ALDH activity, tumorsphere formation under particular culture conditions, and expression of SOX2, Nanog, and Oct4) [60]. Here, POU5F1 is linked to non-small cell lung carcinoma.