KRAS and lung cancer: Next, we analyzed Ninj1 expression in mice harboring lung tumors caused by exposure to carcinogens such as urethane or the combination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene (tobacco carcinogens, TC) [35, 36] (Fig. 1e, S1a) or caused by the oncogenic Kras mutation (KrasG12D/+) that is an established a genetic alteration that is characteristic of lung cancer [37](Fig. 1f).