PIEZO1 and infection: In addition, we observed a strong elevation of the corresponding CaV3.1 (Cacna1g) and CaV3.2 (Cacna1h) channels in MuSCs, in which the floxed Piezo1 alleles were deleted by Ad-Cre infection (Fig. 6D), strongly suggesting that loss of the Piezo1 Ca2+ channel leads to a compensatory increase of T-Type Ca2+ channels.