For example, circ-HuR is underexpressed in GC tissues and cell lines, and mechanically, circ-HuR interferes with CCHC-type zinc finger nucleic acid-binding protein, and thus its binding to HuR promoters is restrained, and as a result, GC cell growth and metastasis are repressed.8 The gene discussed is ELAVL1; the disease is gastric cancer.