Median concentration of α-synuclein EVs was 13,253 Evs/μl (3,880–81,847 min-max) in normal individuals, 11,603 Evs/μl (4,920–43,207 min-max) in individuals with AD dementia, and 12,393 EVs/μl (5,553–47,800 min-max) in individuals with DLB. Here, SNCA is linked to Lewy body dementia.