TAD continued to have a statistically significant (i.e., p < 0.05) impact on ORR and OS in the final multivariable analyses after taking account of over 20 additional parameters to TAD, including tumor size, number of lesions, unilobar vs bilobar disease, BCLC stage, ALBI (Albumin-Bilirubin) score, Child–Pugh score, HCC etiology, and presence of PVT (Online Resource 1, Tables S1, S2, and S3). The gene discussed is ALB; the disease is neoplasm.