We focused on the DEGs that are also highly expressed: LHX1 (associated in Müllerian agenesis; Huang et al., 2014), HOXD8 (homeobox gene that is highly expressed during the development of the chicken MD; Roly et al., 2020), FAM3B (a recently identified FGFR ligand implicated in posterior development; Zhang et al., 2021), NDN, androgen receptor (AR) and GATA5 (expressed during the MD development and associated with abnormalities of the genitourinary tract of female mice; Roly et al., 2020; Molkentin et al., 2000). The gene discussed is LHX1; the disease is Menkes disease.