TLR4 and cardiovascular disorder: It has also been shown that the TLR4/MyD88/NF‐kB signalling pathway plays a very important role in the inflammatory damage to cardiomyocytes caused by cardiovascular diseases such as heart failure (HF) after AMI, myocardial fibrosis (MF), hypoxia/reoxygenation (H/R) and coronary microembolism (CME).13, 14, 15, 16