Combination of CP-673451 treatment and DUSP1 KD induced a reduction in the average neurite-like process length per cell compared to CP-673451 treatment alone in U87 GBM cells (42% (31.1 ± 5.6 μm vs 53.8 ± 8.27 μm (p ≤ 0.01)) and G179 GSCs (30% (13.0 ± 1.1 μm vs 18.5 ± 2.2 μm (p ≤ 0.01)) (Fig. 7A, B). This evidence concerns the gene DUSP1 and glioblastoma.