INS and type 1 diabetes mellitus: Assuming that this strategy would be used in a man in his twenties who is in Japan and has T1DM, and comparing the cost of this procedure with those of other treatments, such as lifelong insulin administration or islet transplantation with lifelong immunosuppressive therapy, although our strategy is expensive to implement, it would be more cost effective in the long term (insulin therapy: USD 619,199; islet transplantation: USD 958,134, and IPCs auto-transplantation: USD 396,353; costs calculated with a diabetologist; data submitted to a journal).