MXRA8 and infection: Among these genes, transfecting of siRNA targeting matrix remodeling associated 8 (MXRA8, also called limitrin, ASP3 or DICAM), a membrane protein that normally interacts with αvβ integrin, associated with the blood-brain barrier and was recently identified as an entry receptor for chikungunya virus (CHIKV)8,15,16, could significantly improve cell viability of Hs578T cells under OVM infection (Fig. 1e).