Circ_0003928, formed by back-splicing of TAO kinase 1 (TAOK1) gene, is one of 10 upregulated circRNAs in high glucose-induced human umbilical vein endothelial cells [11], suggesting that circ_0003928 may be involved in the pathogenesis of DN. This evidence concerns the gene TAOK1 and liver dysplastic nodule.