A case–control study involving 802 autopsy verified PSP patients has discovered that H1d (OR: 1.86), H1g (OR: 3.64) and H1o (OR: 2.60) could lead to the onset of PSP [111], and H2, H1c, H1e, H1q and H1d are related to the severity of tau pathology [111]. Here, MAPT is linked to supranuclear palsy, progressive, 1.