H&E staining of metastatic tissues were shown in Fig. 6H. In addition, H&E staining of tumor tissues in the NC group, NC + DDP group, STC1-sh1 group and STC1-sh1 + DDP group was shown in Supplementary Fig. 6B (H&E staining of tumor tissues in four groups). This evidence concerns the gene STC1 and neoplasm.