In addition, the results of WB analysis demonstrated that the protein expression levels of members in the integrin family (ITGAV, ITGB6 and ITGB7) had decreased in the STC1-sh1 groups compared with the NC groups (Supplementary Fig. 6F (IHC assays of proteins in PI3K signaling pathway in mouse tumor tissues)). This evidence concerns the gene ITGB6 and neoplasm.