AIF1 and hematoma: Double immunofluorescence staining revealed that integrin αVβ5 was mainly expressed in the microglia/macrophages (Iba-1+) in the peri-hematoma tissue at 24 h after ICH, whereas integrin αVβ5 was not co-localized with astrocytes and neurons in the mouse brain (Fig. 1C, D).