HAVCR1 and cervical squamous intraepithelial neoplasia: Furthermore, as shown in Fig. 2B, the expression of the TIM-1 protein was significantly higher in the CC tissue than in the CIN or normal cervical tissue (P < 0.001), and was higher in the CIN tissue than in normal cervical tissue (P < 0.01), and there were no significant differences between the HSIL and LSIL tissue (P = 0.509).