, with age, sex, CAD, BMI, smoking habit, SBP, DBP, TG, TC, LDL, HDL, ALT, AST, GGT, uric acid, creatinine, and FBG as covariates, circulating ADAMTS13 levels positively correlated with AHI, which represents the severity of OSA (β = 7.335/100 ng ADAMTS13, 95%CI = 4.285-10.385, P < 0.001). This evidence concerns the gene GPT and obstructive sleep apnea syndrome.