HELQ and neoplasm: We observed platinum resistance enrichment in the high expression of HELQ (9/15 vs. 3/45, P < 0.001) and XAB2 (7/15 vs. 5/45, P = 0.006) (Figure 2(b)), suggesting that HELQ and XAB2 expressions in ascites tumor cells could be predictors of platinum resistance in HGSC.