ELM analysis revealed that the protein has LIG_14-3-3_1 and LIG_ 14-3-3_3 protein ligands, and cyclin substrates identify sites and PK PKA phosphorylation sites, etc. 14-3-3 proteins are a family of conserved proteins in eukaryotes, which play a role in cell transduction, cell cycle regulation, apoptosis and stress response, and tumor malignant transformation, and are the mediators and regulators of the interaction between proteins. The gene discussed is YWHAQ; the disease is neoplasm.